Introduction

The Epstein–Barr virus is a rare causative pathogen identified in the posterior segment. The majority of cases were presented with a serious condition of acute retinal necrosis, and most of these eyes had poor outcomes. The clinical features and effective treatment options for this condition are still unclear.

Case description: A 10-year-old boy with leukaemia and receiving immunosuppressive regimen presented with decreasing visual acuity to counting fingers in his left eye for 2 weeks. Fundus examination revealed disc swelling, retinitis, retinal exudates and haemorrhages. Aqueous polymerase chain reaction was positive for Epstein–Barr virus DNA but negative for cytomegalovirus, herpes simplex virus and varicella zoster virus DNA. Systemic acyclovir and intravitreal ganciclovir injection were administered. Seven months later, retinitis resolved with remnant retinal fibrosis, and visual acuity improved to 20/500.

Conclusion

Epstein–Barr virus is rarely identified as a sole pathogen in retinitis. Peripapillary predilection might be another type of presenting feature apart from the more-commonly reported peripheral acute retinal necrosis.

中文翻译：

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免疫功能低下儿童的 Epstein-Barr 病毒性视网膜炎：病例报告。

介绍

爱泼斯坦-巴尔病毒是一种罕见的后段病原体。大多数病例出现严重的急性视网膜坏死，并且这些眼睛中的大多数预后不佳。这种情况的临床特征和有效治疗方案仍不清楚。

病例描述：一名患有白血病并接受免疫抑制治疗的 10 岁男孩，因左眼数手指视力下降 2 周就诊。眼底检查显示视盘肿胀、视网膜炎、视网膜渗出液和出血。水性聚合酶链反应对 Epstein-Barr 病毒 DNA 呈阳性，但对巨细胞病毒、单纯疱疹病毒和水痘带状疱疹病毒 DNA 呈阴性。给予全身阿昔洛韦和玻璃体内注射更昔洛韦。七个月后，视网膜炎随着残留的视网膜纤维化消失，视力提高到 20/500。

结论

Epstein-Barr 病毒很少被确定为视网膜炎的唯一病原体。除了更常见的外周急性视网膜坏死之外，视乳头周围的偏好可能是另一种表现特征。