This work describes betanodavirus infection in two species of groupers (family Serranidae) from the Algerian coast: the dusky grouper Epinephelus marginatus and the golden grouper Epinephelus costae . At necropsy, characteristic clinical signs, external injuries, clouded eyes and brain congestion, generally associated with viral encephalopathy and retinopathy (VER) infection were observed. The partial sequences of RNA1 and RNA2 from two viral strains were obtained, and the phylogenetic analysis revealed the presence of the red‐spotted grouper nervous necrosis virus (RGNNV) genotype closely related to strains previously detected in groupers in the same geographic area. Results obtained in this study support the hypothesis that VER disease is endemic in the Algerian grouper population.

中文翻译：

---

病毒性脑病和视网膜病是阿尔及利亚沿海的野生石斑鱼（Epinephelus spp。属）的地方病。

这项工作描述了来自阿尔及利亚海岸的两种石斑鱼（Serranidae家族）中的犬瘟病毒感染：昏暗的石斑鱼Epinephelus marginatus和金色的石斑鱼Epinephelus costae。尸检时，观察到典型的临床体征，外伤，眼睛混浊和脑充血，通常与病毒性脑病和视网膜病（VER）感染有关。从两个病毒株中获得了RNA1和RNA2的部分序列，系统发育分析表明存在与该地区同一地区的石斑鱼先前发现的菌株密切相关的红点石斑鱼神经坏死病毒（RGNNV）基因型。这项研究获得的结果支持以下假设：VER疾病在阿尔及利亚石斑鱼种群中是地方病。