Multicomponent Reactions (MCRs) based on imines are experiencing a growing interest in organic chemistry, due to the availability of different aldehydes and amines, and the versatile and amenable chemical behaviour of imines. This rise in popularity is also due to the impulse given by the development of copper-catalyzed MCRs, as copper is an inexpensive and environmentally-friendly metal that can drive the addition of a third component in providing Mannich-type adducts. This digest paper covers a selection of recent advances in copper-catalyzed imine-based MCRs where the third component is an alkyne, an organoboron reagent, an allene/alkene or a cyanide.

中文翻译：

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铜催化的亚胺基多组分反应的最新进展

基于亚胺的多组分反应（MCR）对有机化学的兴趣与日俱增，这归因于可获得不同的醛和胺，以及亚胺的多用途和适宜的化学行为。这种受欢迎程度的提高还归因于铜催化MCR的发展所带来的推动力，因为铜是一种廉价且环保的金属，可以驱动添加第三组分以提供曼尼希型加合物。该摘要文件介绍了铜催化的基于亚胺的MCR的最新进展，其中的第三种成分是炔烃，有机硼试剂，丙二烯/烯烃或氰化物。