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VX-765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke-induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway.
CNS Neuroscience & Therapeutics ( IF 5.5 ) Pub Date : 2020-05-27 , DOI: 10.1111/cns.13400
Zhezhe Sun 1, 2 , Lei Gu 2, 3 , Ke Wu 1, 2 , Kankai Wang 1, 2 , Junnan Ru 1, 2 , Su Yang 1, 2 , Zhenzhong Wang 4 , Qichuan Zhuge 1, 2 , Lijie Huang 1, 2 , Shengwei Huang 1, 2
Affiliation  

To investigate the protective effect of VX‐765 on human umbilical mesenchymal stem cells (HUMSCs) in stroke and its mechanism.

中文翻译:

VX-765 通过 AMPK/mTOR 信号通路增强人脐带间充质干细胞对中风诱导的细胞凋亡和炎症反应的自噬。

探讨VX-765对脑卒中人脐带间充质干细胞(HUMSCs)的保护作用及其机制。
更新日期:2020-05-27
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