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Current status and perspectives regarding the association between allergic disorders and cancer
IUBMB Life ( IF 4.6 ) Pub Date : 2020-05-26 , DOI: 10.1002/iub.2285
Mohammad Fereidouni 1, 2 , Gordon A Ferns 3 , Afsane Bahrami 2
Affiliation  

While activation of immune system may lead to a lower risk of some diseases, it has been shown that a history of atopic allergic disorders such as asthma, hay fever, eczema, and food allergies could be related to several types of cancer. However, the evidence is not entirely conclusive. Two proposals suggest a possible mechanism for the association between allergic disorders and cancers: immune surveillance and the antigenic stimulation. The association of allergy and cancer may vary by cancer site and the type of exposure. The aim of current review was to summarize the current knowledge of the association between allergic diseases and the risk of cancers with particular emphasis on case–controls and cohort studies to estimate the cancer risk associated with allergy.

中文翻译:

关于过敏性疾病与癌症之间关联的现状和观点

虽然免疫系统的激活可能会降低某些疾病的风险,但已经表明,哮喘、花粉热、湿疹和食物过敏等特应性过敏性疾病的病史可能与多种癌症有关。然而,证据并不完全是决定性的。两项提议提出了过敏性疾病与癌症之间关联的可能机制:免疫监视和抗原刺激。过敏和癌症的关联可能因癌症部位和暴露类型而异。本综述的目的是总结目前关于过敏性疾病与癌症风险之间关联的知识,特别强调病例对照和队列研究,以估计与过敏相关的癌症风险。
更新日期:2020-05-26
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