During the past two decades, continuous flow chemistry has been developed into a mature field as shown by numerous examples in which complex molecules are synthesised. In this review we discuss recent one-flow multistep syntheses to produce active pharmaceutical ingredients (APIs) including challenges and solutions that have been encountered.

中文翻译：

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活性药物成分的连续一流程多步合成

在过去的二十年中，连续流动化学已发展成为一个成熟的领域，如合成复杂分子的众多实例所示。在这篇综述中，我们讨论了最近的单流多步合成以生产活性药物成分（API），包括遇到的挑战和解决方案。