Abstract Introduction: Despite the new SARS-CoV-2 (COVID-19) be the seventh of the coronavirus family viruses known to cause human disease, little is known about potential symptoms and syndromes secondary to the compromise of the central and peripheral nervous systems. We reviewed neurological manifestations due to the new coronavirus, thus far published in the literature, as well as guidelines issued by sub-specialties in Neurology, to tackle the disease. Methods: we searched medical databases, such as PubMed, PubMed Central, LILACS and Google scholar for papers (case reports, short letters, case series, etc) describing neurological symptoms in patients with confirmed or suspect COVID-19 diagnosis and also searched webpages of associations and organizations that deal with neurological disorders. Results: we describe briefly each article considered for this review. Forty-one papers were found associating neurological conditions and COVID-19. Cases are divided by disease groups and, within each disease group, results are listed in chronological order or publication date. We also discuss briefly recommendations for neurological patients, according to disease group. Conclusion: Although there is evidence of neurological manifestations with previous coronaviruses, COVID-19 is assuring a volume of published papers not seen before for other coronavirus infections. Most neurological cases are not life-threatening, but 10 to 20% of cases will require hospitalization and are in risk for sequelae and death. Although a lot of data coming from these papers is amassing, researchers must bear in mind that many papers currently published are not yet peer-reviewed, and thus are prone to further corrections.

中文翻译：

---

COVID-19：对神经系统反应的时间顺序回顾-到2020年5月，我们知道些什么？

摘要简介：尽管新的SARS-CoV-2（COVID-19）是已知可导致人类疾病的冠状病毒家族病毒中的第七种，但对于中枢和周围神经系统受损继发的潜在症状和综合症知之甚少。我们回顾了迄今为止在文献中发表的新冠状病毒引起的神经系统表现，以及由神经内科专业发布的指南来应对这种疾病。方法：我们在医学数据库（例如PubMed，PubMed Central，LILACS和Google Scholar）中搜索了描述确诊或疑似COVID-19诊断的患者的神经系统症状的论文（病例报告，短信，病例系列等），还搜索了处理神经系统疾病的协会和组织。结果：我们简要介绍了本评论考虑的每篇文章。共发现41篇与神经系统疾病和COVID-19相关的论文。病例按疾病组划分，在每个疾病组内，结果按时间顺序或发布日期列出。根据疾病组，我们还将简要讨论对神经系统患者的建议。结论：尽管有证据表明以前的冠状病毒具有神经学表现，但COVID-19可以确保大量其他冠状病毒感染之前未见的发表论文。大多数神经系统疾病不会危及生命，但10％至20％的病例需要住院治疗，并且有后遗症和死亡的风险。尽管来自这些论文的大量数据正在积累，