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Feasibility of proton FLASH irradiation using a synchrocyclotron for preclinical studies.
Medical Physics ( IF 3.8 ) Pub Date : 2020-05-26 , DOI: 10.1002/mp.14253
Arash Darafsheh 1 , Yao Hao 1 , Townsend Zwart 2 , Miles Wagner 2 , Daniel Catanzano 2 , Jeffrey F Williamson 1 , Nels Knutson 1 , Baozhou Sun 1 , Sasa Mutic 1 , Tianyu Zhao 1
Affiliation  

It has been recently shown that radiotherapy at ultrahigh dose rates (>40 Gy/s, FLASH) has a potential advantage in sparing healthy organs compared to that at conventional dose rates. The purpose of this work is to show the feasibility of proton FLASH irradiation using a gantry‐mounted synchrocyclotron as a first step toward implementing an experimental setup for preclinical studies.

中文翻译:

使用同步回旋加速器进行质子FLASH辐照进行临床前研究的可行性。

最近显示,与常规剂量率相比,超高剂量率(> 40 Gy / s,FLASH)放疗在保留健康器官方面具有潜在优势。这项工作的目的是展示使用龙门式同步回旋加速器进行质子FLASH辐射的可行性,这是实现临床前研究实验装置的第一步。
更新日期:2020-05-26
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