当前位置: X-MOL 学术Am. J. Infect. Control › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Pretreated household materials carry similar filtration protection against pathogens when compared with surgical masks.
American Journal of Infection Control ( IF 4.9 ) Pub Date : 2020-05-25 , DOI: 10.1016/j.ajic.2020.05.024
Jonathan M Carnino 1 , Sunhyo Ryu 1 , Kareemah Ni 1 , Yang Jin 1
Affiliation  

Objective

The past 4 months, the emergence and spread of novel 2019 SARS-Cov-2 (COVID-19) has led to a global pandemic which is rapidly depleting supplies of personal protective equipment worldwide. There are currently over 1.6 million confirmed cases of COVID-19 worldwide which has resulted in more the 100,000 deaths. As these numbers grow daily, hospitals are being forced to reuse surgical masks in hopes of conserving their dwindling supply. Since COVID-19 will most likely have effects that last for many months, our nationwide shortage of masks poses a long term issue that must be addressed immediately.

Methods

Based on a previous study by Quan et al., a salt-based soaking strategy has been reported to enhance the filtration ability of surgical masks. We propose a similar soaking process which uses materials widely available in anyone's household. We tested this method of pretreating a variety of materials with a salt-based solution by a droplet test using fluorescently stained nanoparticles similar in size to the COVID-19 virus.

Results

In this study, we found that paper towels and surgical masks pretreated with the salt-based solution showed a noticeable increase in filtration of nanoparticles similar in size to the COVID-19 virus. We also show that the TWEEN20 used by Quan et al. is not a critical component for the solution, and using salt alone in solution still provides a dramatically increased level of protection.

Conclusions

We believe this method will allow for healthcare workers to create a disposable added layer of protection to their surgical masks, N95s, or homemade masks by using household available products. Adoption of this method may play an essential role in ensuring the safety of healthcare workers during the COVID-19 pandemic and any pandemics that may arise in the future.



中文翻译:

与外科口罩相比,经过预处理的家用材料对病原体具有相似的过滤保护作用。

客观的

过去 4 个月,新型 2019 年 SARS-Cov-2 (COVID-19) 的出现和传播导致全球大流行,全球范围内的个人防护设备供应迅速枯竭。目前全球有超过 160 万例 COVID-19 确诊病例,导致超过 100,000 人死亡。随着这些数字每天都在增长,医院被迫重复使用外科口罩,以期保住日益减少的供应。由于 COVID-19 很可能会产生持续数月的影响,因此我们全国范围内的口罩短缺构成了一个必须立即解决的长期问题。

方法

根据 Quan 等人先前的一项研究,据报道,一种基于盐的浸泡策略可以增强外科口罩的过滤能力。我们提出了一种类似的浸泡过程,该过程使用任何人家中广泛使用的材料。我们使用大小与 COVID-19 病毒相似的荧光染色纳米粒子,通过液滴测试测试了这种用盐基溶液预处理各种材料的方法。

结果

在这项研究中,我们发现用盐基溶液预处理的纸巾和外科口罩显示出与 COVID-19 病毒大小相似的纳米颗粒的过滤显着增加。我们还展示了 Quan 等人使用的 TWEEN20。不是溶液的关键成分,在溶液中单独使用盐仍可提供显着提高的保护水平。

结论

我们相信这种方法将允许医护人员通过使用家用产品为他们的外科口罩、N95 或自制口罩创建一个一次性的附加保护层。在 COVID-19 大流行和未来可能出现的任何大流行期间,采用这种方法可能在确保医护人员的安全方面发挥重要作用。

更新日期:2020-07-25
down
wechat
bug