Purpose

To compare retrospectively two different techniques of Xen implantation, which are transconjunctival (ab-externo) and standard (ab-interno) techniques.

Methods

Forty-three eyes of 43 patients with primary open-angle glaucoma (POAG) who had Xen implantation operation via transconjunctival (ab-externo) technique comprised Group 1. Of the 43 patients, 20 (46.5%) were males and 23 (53.5%) were females. Their mean age was 61.76 ± 8.81 (41–74) years. Forty-four eyes of 44 patients with POAG who had Xen implantation operation via standard (ab-interno) technique comprised Group 2. Of the 44 patients, 21 (47.7%) were males and 23 (52.3%) were females. The mean age of this group was 63.80 ± 9.78 (38–75) years.

Results

Regarding age and sex, there were no significant differences between the groups (p > 0.05). The mean postoperative 1st day, 1st week, 1st month, 3rd month, 6th month, and 12th month IOPs were significantly lower than the mean preoperative IOP in both groups (p < 0.05). The mean number of anti-glaucomatous agents used postoperatively was significantly lower than the mean preoperative number for both groups (p < 0.05). There was a significantly smaller need for needling in the transconjunctival group (p < 0.05).

Conclusion

Xen implantation is a safe and effective method of reducing IOP and anti-glaucomatous dependence. Potential postoperative complications can be resolved easily. There were no significant differences between the standard method and the transconjunctival method in respect of IOP and re-use of anti-glaucomatous agents. However, there was a significantly smaller need for needling in the transconjunctival group. We recommend further studies to investigate long-term results.

中文翻译：

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原发性开角型青光眼患者的Xen植入：两种不同技术的比较。

目的

回顾性地比较两种不同的Xen植入技术，即透结膜（ab-externo）和标准（ab-interno）技术。

方法

通过结膜（ab-externo）技术进行Xen植入手术的43例原发性开角型青光眼（POAG）患者的43眼组成第1组。在43例患者中，男性20例（46.5％）和23例（53.5％） ）是女性。他们的平均年龄为61.76±8.81（41–74）岁。通过标准（ab-interno）技术进行Xen植入手术的44例POAG患者中的44只眼属于第2组。在44例患者中，男性21例（47.7％），女性23例（52.3％）。该组的平均年龄为63.80±9.78（38-75）岁。

结果

关于年龄和性别，两组之间无显着差异（p  > 0.05）。两组患者术后第一天，第一周，第一个月，第三个月，第六个月和十二个月的平均眼压均显着低于两组术前平均眼压（p  <0.05）。术后平均使用抗青光眼药物的数量均显着低于两组的术前平均药物数量（p  <0.05）。经结膜组的针刺需求明显减少（p  <0.05）。

结论

Xen植入是减少IOP和抗青光眼依赖性的一种安全有效的方法。潜在的术后并发症可以轻松解决。就眼压和抗青光眼药的重复使用而言，标准方法和结膜透皮法之间没有显着差异。然而，结膜组的针刺需求明显减少。我们建议进行进一步的研究以调查长期结果。