当前位置:
X-MOL 学术
›
J Chromatogr Sci
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Collection and Separation of Fleroxacin and Ciprofloxacin in Ultrasound-Assisted Ionic Liquid Salting-Out Microextraction System.
Journal of Chromatographic Science ( IF 1.3 ) Pub Date : 2020-05-25 , DOI: 10.1093/chromsci/bmaa021 Kai Li 1 , Zhongling Liu 2 , Yue Liu 2 , Hanqi Zhang 3 , Wei Yu 4
Journal of Chromatographic Science ( IF 1.3 ) Pub Date : 2020-05-25 , DOI: 10.1093/chromsci/bmaa021 Kai Li 1 , Zhongling Liu 2 , Yue Liu 2 , Hanqi Zhang 3 , Wei Yu 4
Affiliation
An ultrasound-assisted ionic liquid (IL) salting-out microextraction system was developed and applied for the extraction of quinolone antibiotics from urine. A precipitate was formed from the salt and IL, and it acted as the sorbent for the analytes. The precipitate containing the analyte was separated by filtration, redissolved, and the solution then was evaporated. The resulting extract was redissolved for high-performance liquid chromatographic analysis. Several parameters, including type and volume of IL, the type and amount of salts, sample pH, temperature and extraction time were optimized. Under the optimal experimental conditions, the limits of detection for fleroxacin and ciprofloxacin were 3.12 and 4.97 μg L−1, respectively. When the present method was applied to real urine sample analysis, the analyte recoveries ranged from 82.3 to 106.8%. This ultrasound-assisted IL salting-out microextraction system had the characteristics of high recoveries, shorter separation time and easy-to-perform collection procedure, which yielded the method to have potential for wide application.
中文翻译:
超声辅助离子液体盐析微萃取系统中氟罗沙星和环丙沙星的收集和分离。
开发了超声辅助离子液体盐析微萃取系统,并将其用于从尿液中提取喹诺酮类抗生素。由盐和IL形成沉淀物,并充当分析物的吸附剂。通过过滤分离含有分析物的沉淀物,再溶解,然后将溶液蒸发。将所得提取物重新溶解,以进行高效液相色谱分析。优化了几个参数,包括IL的类型和体积,盐的类型和数量,样品的pH,温度和提取时间。在最佳实验条件下,氟沙星和环丙沙星的检出限分别为3.12和4.97μgL -1, 分别。当本方法用于实际尿液样品分析时,分析物的回收率在82.3至106.8%的范围内。该超声辅助IL盐析微萃取系统具有回收率高,分离时间短,易于收集的特点,从而具有广泛的应用前景。
更新日期:2020-05-25
中文翻译:
超声辅助离子液体盐析微萃取系统中氟罗沙星和环丙沙星的收集和分离。
开发了超声辅助离子液体盐析微萃取系统,并将其用于从尿液中提取喹诺酮类抗生素。由盐和IL形成沉淀物,并充当分析物的吸附剂。通过过滤分离含有分析物的沉淀物,再溶解,然后将溶液蒸发。将所得提取物重新溶解,以进行高效液相色谱分析。优化了几个参数,包括IL的类型和体积,盐的类型和数量,样品的pH,温度和提取时间。在最佳实验条件下,氟沙星和环丙沙星的检出限分别为3.12和4.97μgL -1, 分别。当本方法用于实际尿液样品分析时,分析物的回收率在82.3至106.8%的范围内。该超声辅助IL盐析微萃取系统具有回收率高,分离时间短,易于收集的特点,从而具有广泛的应用前景。