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Clinical research methods for treatment, diagnosis, prognosis, etiology, screening, and prevention: A narrative review.
Journal of Evidence-Based Medicine ( IF 7.3 ) Pub Date : 2020-05-01 , DOI: 10.1111/jebm.12384
Xiaomei Yao 1, 2, 3 , Ivan D Florez 3, 4 , Ping Zhang 5 , Chongfan Zhang 2 , Yi Zhang 6 , Chunxue Wang 7 , Xiaofang Liu 8 , Xiuhong Nie 9 , Bing Wei 9 , Michelle A Ghert 1, 10
Affiliation  

This narrative review is an introduction for health professionals on how to conduct and report clinical research on six categories: treatment, diagnosis/differential diagnosis, prognosis, etiology, screening, and prevention. The importance of beginning with an appropriate clinical question and the exploration of how appropriate it is through a literature search are explained. There are three methodological directives that can assist clinicians in conducting their studies from a methodological perspective: (1) how to conduct an original study or a systematic review, (2) how to report an original study or a systematic review, and (3) how to assess the quality or risk of bias for a previous relevant original study or systematic review. This methodological overview article would provide readers with the key points and resources regarding how to perform high‐quality research on the six main clinical categories.

中文翻译:

治疗,诊断,预后,病因,筛查和预防的临床研究方法:叙述性评论。

这篇叙述性综述为卫生专业人员介绍了如何进行和报告以下六类临床研究:治疗,诊断/鉴别诊断,预后,病因,筛查和预防。解释了从适当的临床问题开始的重要性以及通过文献检索探索适当性的重要性。可以从方法学角度帮助临床医生进行研究的三种方法学指导:(1)如何进行原始研究或系统评价,(2)如何报告原始研究或系统评价,以及(3)如何评估先前相关原始研究或系统评价的质量或偏倚风险。
更新日期:2020-05-01
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