The malfunctioning of semicircular canals (SCCs) in the vestibular system results in diseases that disrupt the individual’s daily life. Vestibular diseases can be treated more effectively if the functioning of the SCCs is better understood. However, the SCC is difficult to dissect, because it is a complex structure buried deep in the inner ear. To thoroughly understand the function of SCCs and provide better treatment plans for vestibular diseases, we constructed a numerical model of human SCCs and validated it experimentally. Based on the principle of the vestibulo-ocular reflex, the cupula deformation deflects embedded sensory hair cell bundles, transmitting signals to the brain and inducing a slow compensatory eye movement. The slow-phase velocity (SPV) is the characteristic of the slow compensatory eye movement. We investigated the cupula deformation in the numerical model and the SPV under different conditions. The relationship between the cupula deformation and the SPV was quantified for three volunteers. It was observed that the maximal cupula deformation is proportional to the angular acceleration, while the SPV is changing nonlinearly with the angular acceleration. For three volunteers, the relationship between the cupula deformation and the SPV can be expressed by same type function of which the parameters are dependent on individual differences. These results validate the reliability of the numerical model.

前庭系统中半规管 (SCC) 的故障会导致疾病，扰乱个人的日常生活。如果更好地了解 SCC 的功能，则可以更有效地治疗前庭疾病。然而，SCC 很难解剖，因为它是深埋在内耳中的复杂结构。为了彻底了解 SCC 的功能并为前庭疾病提供更好的治疗方案，我们构建了人类 SCC 的数值模型并对其进行了实验验证。基于前庭眼反射的原理，罩杯变形使嵌入的感觉毛细胞束偏转，将信号传输到大脑并引起缓慢的补偿性眼球运动。慢相速度 (SPV) 是慢代偿性眼球运动的特征。我们研究了数值模型和 SPV 在不同条件下的杯形变形。对三名志愿者的杯形变形和 SPV 之间的关系进行了量化。观察到最大杯形变形与角加速度成正比，而 SPV 随角加速度非线性变化。对于三名志愿者来说，杯形变形与 SPV 之间的关系可以用同类型函数来表示，其参数依赖于个体差异。这些结果验证了数值模型的可靠性。观察到最大杯形变形与角加速度成正比，而 SPV 随角加速度非线性变化。对于三名志愿者来说，杯形变形与 SPV 之间的关系可以用同类型函数来表示，其参数依赖于个体差异。这些结果验证了数值模型的可靠性。观察到最大杯形变形与角加速度成正比，而 SPV 随角加速度非线性变化。对于三名志愿者来说，杯形变形与 SPV 之间的关系可以用同类型函数来表示，其参数依赖于个体差异。这些结果验证了数值模型的可靠性。