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Thoracic duct identification with indocyanine green fluorescence during minimally invasive esophagectomy with patient in prone position.
Diseases of the Esophagus ( IF 2.6 ) Pub Date : 2020-05-25 , DOI: 10.1093/dote/doaa030
Massimo Vecchiato 1 , Antonio Martino 1 , Massimo Sponza 2 , Alessandro Uzzau 1 , Antonio Ziccarelli 1 , Federico Marchesi 3 , Roberto Petri 1
Affiliation  

Chylothorax is a serious complication of transthoracic esophagectomy. Intraoperative thoracic duct (TD) identification represents a possible tool for preventing or repairing its lesions, and it is most of the time difficult, even during high-definition thoracoscopy. The aim of the study is to demonstrate the feasibility of using near-infrared fluorescence-guided thoracoscopy to identify TD anatomy and check its intraoperative lesions during minimally invasive esophagectomy. A 0.5 mg/kg solution of indocyanine green (ICG) was injected percutaneously in the inguinal nodes of 19 patients undergoing minimally invasive esophagectomy in a prone position, before thoracoscopy. TD anatomy and potential intraoperative lesions were checked with the KARL STORZ OPAL1® Technology. In all of the 19 patients where transthoracic esophagectomy was feasible, the TD was clearly identified after a mean of 52.7 minutes from injection time. The TD was cut for oncological radicality in two patients, and it was successfully ligated under the ICG guide. No postoperative chylothorax or adverse reactions from the ICG injection occurred. The TD identification with indocyanine green fluorescence during minimally invasive esophagectomy is a simple, effective, and non-time-demanding tool; it may become a standard procedure to prevent postoperative chylothorax.

中文翻译:

在患者处于俯卧位的微创食管切除术中,用吲哚菁绿荧光进行胸导管鉴别。

胸廓胸部切除术是经胸食管切除术的严重并发症。术中胸导管(TD)识别是预防或修复其病变的一种可能工具,即使在高清晰度的胸腔镜检查期间,多数情况下也很困难。该研究的目的是证明在微创食管切除术中使用近红外荧光引导的胸腔镜检查识别TD解剖结构并检查其术中病变的可行性。在胸腔镜检查前,经俯卧位经微创食管切除术的19例患者的腹股沟皮内注射了0.5 mg / kg的吲哚菁绿(ICG)溶液。使用KARL STORZOPAL1®技术检查TD解剖结构和术中潜在病变。在19例行胸腔食管切除术可行的患者中,在距注射时间平均52.7分钟之后,可以清楚地确定TD。TD因两名患者的肿瘤学根治性而被切除,并在ICG指南下成功结扎。术后未发生乳糜胸或ICG注射引起的不良反应。在微创食管切除术中用吲哚菁绿荧光进行TD鉴定是一种简单,有效且无时间要求的工具。它可能成为预防术后乳糜胸的标准程序。在微创食管切除术中用吲哚菁绿荧光进行TD鉴定是一种简单,有效且无时间要求的工具。它可能成为预防术后乳糜胸的标准程序。在微创食管切除术中用吲哚菁绿荧光进行TD鉴定是一种简单,有效且无时间要求的工具。它可能成为预防术后乳糜胸的标准程序。
更新日期:2020-05-25
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