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Human cancer germline antigen-specific cytotoxic T cell-what can we learn from patient.
Cellular & Molecular Immunology ( IF 24.1 ) Pub Date : 2020-05-25 , DOI: 10.1038/s41423-020-0468-x
Megat Abd Hamid 1 , Yanchun Peng 1, 2 , Tao Dong 1, 2
Affiliation  

In this review, we will highlight the importance of cancer germline antigen-specific cytotoxic CD8+ T lymphocytes (CTL) and the factors affecting antitumor CTL responses. In light of cancer immunotherapy, we will emphasis the need to further understand the features, characteristics, and actions of modulatory receptors of human cancer germline-specific CTLs, in order to determine the optimal conditions for antitumor CTL responses.



中文翻译:

人类癌症生殖系抗原特异性细胞毒性T细胞-我们可以从患者那里学到什么。

在这篇综述中,我们将强调癌症种系抗原特异性细胞毒性CD8 + T淋巴细胞(CTL)的重要性以及影响抗肿瘤CTL反应的因素。根据癌症免疫疗法,我们将强调需要进一步了解人类癌症种系特异性CTL的调节受体的特征,特征和作用,以便确定抗肿瘤CTL反应的最佳条件。

更新日期:2020-05-25
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