Abstract

Background

One of the most common problems associated with cardiovascular diseases (CVDs) is cognitive impairments (CIs) leading to reduced quality of life and treatment adherence in patients. The aim of this systematic review was to examine the effects of cardiac rehabilitation (CR) on cognitive function in CVD patients.

Material and method

PubMed, Scopus, Web of Science and Ovid MEDLINE databases were searched for identification the relevant studies without language restriction. We included the studies published from root to August 2019, evaluating the effects of CR on at least one type of cognitive functions through valid neuropsychological tests. Finally, nine studies with different study designs were entered in this systematic review. The full texts of these studies were critically appraised with various quality assessment tools.

Result

Patients were evaluated by different cognitive domains including global cognition, attention, executive function, memory and language prior to and following CR program among included studies. Most of the included studies reported significant cognitive improvement of the attention/executive function and memory domains. Two studies showed statistically significant improvement in global cognition using Modified Mini-Mental State (3MS) and Montreal Cognitive Assessment (MoCA) tools. Similar effects were not found in language domain.

Conclusion

It seems that cognitive impairments in CVD patients can be improved with CR program. Because this review is limited by low number of included studies, and there were various study designs without control groups, the results should be generalized cautiously. Further studies are recommended.

中文翻译：

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心脏康复对心血管疾病患者认知障碍的影响：系统评价

摘要

背景

与心血管疾病 (CVD) 相关的最常见问题之一是认知障碍 (CI)，导致患者的生活质量和治疗依从性降低。本系统评价的目的是检查心脏康复 (CR) 对 CVD 患者认知功能的影响。

材料和方法

搜索 PubMed、Scopus、Web of Science 和 Ovid MEDLINE 数据库以识别相关研究，没有语言限制。我们纳入了从根源到 2019 年 8 月发表的研究，通过有效的神经心理学测试评估了 CR 对至少一种认知功能的影响。最后，本系统评价纳入了 9 项不同研究设计的研究。使用各种质量评估工具对这些研究的全文进行了严格评估。

结果

在纳入的研究中，患者在 CR 计划之前和之后通过不同的认知领域进行评估，包括全局认知、注意力、执行功能、记忆和语言。大多数纳入的研究报告了注意力/执行功能和记忆领域的显着认知改善。两项研究显示，使用改良的迷你精神状态 (3MS) 和蒙特利尔认知评估 (MoCA) 工具可以显着改善全球认知。在语言领域没有发现类似的效果。

结论

似乎可以通过 CR 计划改善 CVD 患者的认知障碍。由于本综述受限于纳入研究数量少，且研究设计多样且无对照组，因此应谨慎推广结果。建议进一步研究。