Abstract

Purpose

The aim of this study was to investigate the hemodynamic characteristics of posterior circulation infarction (PCI) patients with the vertebral artery dominance (VAD) using Color Doppler flow imaging (CDFI) and Transcranial Doppler sonography (TCD) and to explore the pathogenesis of PCI caused by VAD.

Materials and methods

A total of 186 consecutive PCI patients were enrolled. All the patients underwent magnetic resonance (MR) examination and the clinical data were collected. According to the brain magnetic resonance angiography (MRA), the patients were divided into VAD and non-VAD groups. CDFI and TCD were performed to identify the hemodynamic parameters of the vertebral artery (VA) and basilar artery (BA).

Results

The male population was significantly more frequent in the VAD group (71.3%) as compared to the non-VAD group (53.1%). The significant difference in hemodynamic parameters was observed between VAD and non-VAD groups. Resistance index (RI) of extracranial and intracranial VA was different as well. There were also differences in the VA side-to-side diameter difference-value, peak velocity (Vp), mean velocity (Vm) and pulsatility index (PI) with varying degrees of BA curvature.

Conclusions

VA and BA hemodynamic changes caused by VAD may be an important risk factor in the process of occurrence of PCI. The combination of CDFI and TCD can help to detect the hemodynamic changes in the intracranial and extracranial segments of VA and BA. This can have important clinical value in understanding the pathogenesis of PCI.

中文翻译：

---

彩色多普勒血流显像和经颅多普勒超声对椎动脉优势型后循环梗死患者血流动力学特征的评价

摘要

目的

本研究旨在利用彩色多普勒血流显像（CDFI）和经颅多普勒超声（TCD）研究椎动脉优势（VAD）后循环梗死（PCI）患者的血流动力学特征，并探讨PCI引起的发病机制。通过 VAD。

材料和方法

共招募了 186 名连续 PCI 患者。所有患者均进行磁共振（MR）检查并收集临床资料。根据脑磁共振血管造影（MRA），将患者分为VAD组和非VAD组。进行 CDFI 和 TCD 以确定椎动脉 (VA) 和基底动脉 (BA) 的血流动力学参数。

结果

与非 VAD 组 (53.1%) 相比，VAD 组的男性人群 (71.3%) 显着更高。在 VAD 和非 VAD 组之间观察到血流动力学参数的显着差异。颅外和颅内VA的阻力指数（RI）也不同。VA 侧径差值、峰值速度 (Vp)、平均速度 (Vm) 和脉动指数 (PI) 也存在差异，BA 曲率不同。

结论

VAD引起的VA和BA血流动力学变化可能是PCI发生过程中的重要危险因素。CDFI和TCD联合可以帮助检测VA和BA颅内段和颅外段的血流动力学变化。这对于了解 PCI 的发病机制具有重要的临床价值。