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Regorafenib in previously treated advanced hepatocellular carcinoma: Impact of prior immunotherapy and adverse events.
Liver International ( IF 6.7 ) Pub Date : 2020-05-25 , DOI: 10.1111/liv.14496
Changhoon Yoo 1 , Seonggyu Byeon 2, 3 , Yeonghak Bang 1 , Jaekyung Cheon 4 , Jin W Kim 5 , Jee H Kim 5 , Hong J Chon 6 , Beodeul Kang 6 , Myoung J Kang 7 , Ilhwan Kim 7 , Jun-Eul Hwang 8 , Jung H Kang 9 , Myung A Lee 10 , Jung Y Hong 2 , Ho Y Lim 2 , Baek-Yeol Ryoo 1
Affiliation  

Regorafenib demonstrated a clinical benefit for patients with unresectable hepatocellular carcinoma (uHCC) in the phase III RESORCE trial. Considering the heterogeneity of uHCC and discrepancies in its characteristics between prospective trials and daily practice, real‐life evidence is necessary.

中文翻译:

瑞格非尼在先前治疗的晚期肝细胞癌中的作用:先前免疫治疗和不良事件的影响。

雷戈非尼在RESORCE III期临床试验中显示出对不可切除的肝细胞癌(uHCC)患者的临床益处。考虑到uHCC的异质性和前瞻性试验与日常实践之间的差异,现实生活中的证据是必要的。
更新日期:2020-05-25
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