Efficient and energy‐saving separation of benzene isomers bearing a diverse range of functional groups is a great challenge due to their overlapping physicochemical properties. Here, we report the successfully use of a water‐soluble pillar[5]arene (WP5) as a multifunctional material for the separation and detection of meta /ortho ‐substituted benzene isomers in water. A liquid‐liquid extraction strategy was used for the separation of these benzene isomers based on their different affinity for WP5 in water. The selectivities for the meta over the ortho isomer for xylenes, chlorotoluene, and bromotoluene was 88.6 %, 88.3 %, and 95.0 % respectively, in one extraction cycle. Furthermore, a fluorescence indicator system based on WP5 and a fluorescent dye molecule (10‐methylacridinium, D) was adopted and exhibited significant fluorescence and optical discrimination upon the addition of meta ‐ compared to ortho ‐xylene, which implies that a simple “turn‐on” detection can be performed prior to engaging in the separation process.

中文翻译：

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水溶性支柱[5]芳烃的分离和检测间位和邻位取代的苯异构体。

高效且节能的分离具有多种官能团的苯异构体是一项巨大的挑战，因为它们具有重叠的理化特性。在此，我们报道了成功地使用水溶性柱[5]芳烃（WP5）的作为多功能材料的分离和检测元/邻位取代的苯的异构体中的水。基于这些苯异构体对水中WP5的不同亲和力，采用液-液萃取策略分离这些苯异构体。对于该选择性元在邻在一个萃取循环中，二甲苯，氯甲苯和溴甲苯的异构体分别为88.6％，88.3％和95.0％。此外，采用了基于WP5和荧光染料分子（10-甲基ac基，D）的荧光指示剂系统，与邻二甲苯相比，添加间-后显示出显着的荧光和光学辨别力，这意味着简单的“转弯-可以在参与分离过程之前执行“打开”检测。