Abstract As the field of biomedical engineering has become more precise and sophisticated, the demand for highly-functionalized biomaterials has risen. In particular, novel organic/inorganic hybrid biomaterials with two or more chemical, physical, and optical properties are currently being developed and applied in various biomedical fields. In this review, we classify recently created advanced organic/inorganic hybrid nanomaterials as nanoparticles and nanocomposites and describe their structures, characteristics, and advantages. In addition, we outline the most recent trends in smart organic/inorganic hybrid nanomaterials and nanocomposites (bulk materials) in the fields of medical applications. Finally, we discuss the future direction of the nanomaterials and nanocomposites from the standpoint of current technology and its limitations. Functional organic/inorganic hybrid nanomaterials and nanocomposites, which have both physicochemical properties of organic and inorganic materials, have the potential for use as advanced biomaterials in various biomedical fields, with the ultimate goal of efficiently diagnosing and treating various human diseases.

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用于生物医学应用的高级混合纳米材料

摘要 随着生物医学工程领域的精密化和精细化，对高功能化生物材料的需求不断增加。特别是，具有两种或多种化学、物理和光学特性的新型有机/无机杂化生物材料目前正在开发并应用于各种生物医学领域。在这篇综述中，我们将最近创建的先进有机/无机混合纳米材料归类为纳米粒子和纳米复合材料，并描述了它们的结构、特性和优势。此外，我们概述了医疗应用领域中智能有机/无机混合纳米材料和纳米复合材料（散装材料）的最新趋势。最后，我们从当前技术及其局限性的角度讨论了纳米材料和纳米复合材料的未来发展方向。