Objective

We evaluated the effects of music therapy on pain, depression and quality of life in patients with fibromyalgia.

Methods

Ten online databases were searched to identify randomized controlled trials that investigated the effects of music therapy on fibromyalgia patients, published up to 1st January 2019. The results were filtered and independently extracted. Statistical heterogeneity was assessed using the chi-square test. According to the outcome of the heterogeneity indices, either a fixed effect or a random effect model was used.

Results

In total, seven randomized controlled trials were included. The Pain Visual Analog Scale, the McGill Pain Scale, the Beck Depression Scale and the Fibromyalgia Impact Questionnaire were used as outcome measures. Our evidence indicated that patient intervention with music therapy had lower scores on the Pain Visual Analog Scale (95% confidence interval [CI] -2.22 to -1.18, Z = 6.44, P < 0.00001, four studies) and Beck Depression Scale (95% CI -0.65 to -0.03, Z = 2.17, P = 0.03, two studies). No significant differences were observed on the McGill Pain Scale between the music intervention and control groups (95% CI -0.83 to -0.09, Z = 1.59, P = 0.11). A general qualitative description of the Fibromyalgia Impact Questionnaire results was given due to high heterogeneity (I² = 96%, P < 0.00001).

Conclusions

The music therapy is superior to non-music therapy in the treatment of pain, depression, and improvement of quality of life in fibromyalgia patients. However, due to the low quantity and quality of the included studies, a larger number and high-quality of RCTs are needed to confirm the beneficial effects of music therapy.

中文翻译：

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基于音乐的改善纤维肌痛综合征的干预措施：荟萃分析。

客观的

我们评估了音乐疗法对纤维肌痛患者的疼痛、抑郁和生活质量的影响。

方法

搜索了 10 个在线数据库，以确定截至 2019 年 1 月 1 日发布的随机对照试验，这些试验调查了音乐疗法对纤维肌痛患者的影响。结果经过过滤和独立提取。使用卡方检验评估统计异质性。根据异质性指数的结果，使用固定效应或随机效应模型。

结果

总共包括七项随机对照试验。疼痛视觉模拟量表、麦吉尔疼痛量表、贝克抑郁量表和纤维肌痛影响问卷用作结果测量。我们的证据表明，音乐治疗的患者干预在疼痛视觉模拟量表（95% 置信区间 [CI] -2.22 至 -1.18，Z = 6.44，P < 0.00001，四项研究）和贝克抑郁量表（95% CI -0.65 至 -0.03，Z = 2.17，P = 0.03，两项研究）。音乐干预组和对照组之间在麦吉尔疼痛量表上没有观察到显着差异（95% CI -0.83 至 -0.09，Z = 1.59，P = 0.11）。由于高异质性（I ²  = 96%，P < 0.00001），给出了纤维肌痛影响问卷结果的一般定性描述。

结论

音乐疗法在治疗纤维肌痛患者的疼痛、抑郁和改善生活质量方面优于非音乐疗法。然而，由于纳入研究的数量和质量较低，需要更多数量和高质量的 RCT 来证实音乐疗法的有益效果。