Tissue engineering (TE) provides a practicable method for tissue and organ repair or substitution. As the most important component of TE, a scaffold plays a critical role in providing a growing environment for cell proliferation and functional differentiation as well as good mechanical support. And the restorative effects are greatly dependent upon the nature of the scaffold including the composition, morphology, structure, and mechanical performance. Medical textiles have been widely employed in the clinic for a long time and are being extensively investigated as TE scaffolds. However, unfortunately, the advantages of textile technology cannot be fully exploited in tissue regeneration due to the ignoring of the diversity of fabric structures. Therefore, this review focuses on textile-based scaffolds, emphasizing the significance of the fabric design and the resultant characteristics of cell behavior and extracellular matrix reconstruction. The structure and mechanical behavior of the fabrics constructed by various textile techniques for different tissue repairs are summarized. Furthermore, the prospect of structural design in the TE scaffold preparation was anticipated, including profiled fibers and some unique and complex textile structures. Hopefully, the readers of this review would appreciate the importance of structural design of the scaffold and the usefulness of textile-based TE scaffolds in tissue regeneration.

中文翻译：

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基于纺织品的组织工程支架的构建和应用：综述。

组织工程（TE）提供了一种可行的组织和器官修复或替代方法。作为TE最重要的组成部分，支架在为细胞增殖和功能分化提供良好的环境以及良好的机械支持方面起着至关重要的作用。恢复作用在很大程度上取决于支架的性质，包括组成，形态，结构和机械性能。医用纺织品在临床上已广泛使用了很长一段时间，并已被广泛研究为TE支架。然而，不幸的是，由于忽略了织物结构的多样性，因此无法在组织再生中充分利用纺织技术的优势。因此，这篇评论主要针对基于纺织品的脚手架，强调织物设计的重要性以及细胞行为和细胞外基质重建的最终特征。总结了通过各种纺织技术构建的用于不同组织修复的织物的结构和机械性能。此外，预计在TE支架制备中进行结构设计的前景，包括异形纤维和一些独特而复杂的纺织品结构。希望这篇评论的读者能够理解支架的结构设计的重要性，以及基于纺织品的TE支架在组织再生中的有用性。总结了通过各种纺织技术构建的用于不同组织修复的织物的结构和机械性能。此外，预计在TE支架制备中进行结构设计的前景，包括异形纤维和一些独特而复杂的纺织品结构。希望这篇评论的读者能够理解支架的结构设计的重要性，以及基于纺织品的TE支架在组织再生中的有用性。总结了通过各种纺织技术构建的用于不同组织修复的织物的结构和机械性能。此外，预计在TE支架制备中进行结构设计的前景，包括异形纤维和一些独特而复杂的纺织品结构。希望这篇评论的读者能够理解支架的结构设计的重要性，以及基于纺织品的TE支架在组织再生中的有用性。