Among patients hospitalized for novel coronavirus disease (COVID-19), between 10 and 14% develop an acute kidney injury and around half display marked proteinuria and haematuria. Post-mortem analyses of COVID-19 kidney tissue suggest that renal tubular cells and podocytes are affected. Here we report two cases of collapsing glomerulopathy and tubulointerstitial lesions in living COVID-19 patients. Despite our use of sensitive reverse transcription polymerase chain reaction techniques in this study, we failed to detect the virus in blood, urine and kidney tissues. Our observations suggest that these kidney lesions are probably not due to direct infection of the kidney by severe acute respiratory syndrome coronavirus 2.

中文翻译：

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严重急性呼吸系统综合症冠状病毒2对冠状病毒病患者肾脏的间接作用。

在因新型冠状病毒病（COVID-19）住院的患者中，有10％至14％会发展为急性肾损伤，大约一半会出现明显的蛋白尿和血尿。死后对COVID-19肾脏组织的分析表明，肾小管细胞和足细胞受到了影响。在这里，我们报告了2例活着的COVID-19患者中的肾小球塌陷和肾小管间质病变。尽管我们在这项研究中使用了敏感的逆转录聚合酶链反应技术，但我们未能在血液，尿液和肾脏组织中检测到该病毒。我们的观察结果表明，这些肾脏病变可能不是由于严重急性呼吸系统综合症冠状病毒2直接感染肾脏引起的。