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Fractionation of phytocannabinoids from industrial hemp residues with high-pressure technologies
The Journal of Supercritical Fluids ( IF 3.9 ) Pub Date : 2020-05-24 , DOI: 10.1016/j.supflu.2020.104898
Erika Vági , Margit Balázs , Attila Komoczi , Máté Mihalovits , Edit Székely

Cannabidiol (CBD) and cannabidiolic acid (CBDA)- rich extracts were obtained from industrial hemp threshing residues by sub- and supercritical carbon dioxide extraction. The supercritical CO2 extraction yielded 2.5–9.2 g/100 g of lipophilic raw extracts containing 0.2–1.8 g of cannabinoids per 100 g of various threshing residues. Carrying out the supercritical extraction with fractionation, the extract from the 1st separator (operated at 8 MPa and 40 °C) contained 30 times more CBD than the extract from the 2nd separator. Applying ethanol cosolvent to scCO2 in 10% (w/w) increased the extraction yield and the yield of main cannabinoids by 30%. Subcritical CO2 extraction resulted in a yield of 2.5 g/100 g dry material with high CBD content (0.9 g/100 g dry threshing residue) in an extract with less complexity and produced with 18% less solvent usage at mild conditions (8 MPa and 27 °C). The recovery of high cannabinoid-content extracts from industrial hemp residues makes this waste suitable for producing value-added extracts for either cosmetic or food industry.



中文翻译:

利用高压技术从工业大麻残留物中分离植物大麻素

通过次临界和超临界二氧化碳萃取从工业大麻脱粒残留物中获得富含大麻二酚(CBD)和大麻二酚酸(CBDA)的提取物。超临界CO 2萃取可得到2.5-9.2 g / 100 g亲脂性粗提物,每100 g各种脱粒残留量均含有0.2-1.8 g大麻素。通过分馏进行超临界萃取,第一分离器(在8 MPa和40°C下操作)的萃取物中CBD含量比第二分离器的萃取物高30倍。将乙醇助溶剂以10%(w / w)的浓度应用于scCO 2可使提取率和主要大麻素的产率提高30%。亚临界CO 2萃取可在萃取物中获得2.5 g / 100 g具有高CBD含量的干物质(0.9 g / 100 g干脱粒残留物)的产量,其复杂性较低,在温和条件下(8 MPa和27° C)。从工业大麻残留物中回收高含量大麻素的提取物,使这种废物适合用于生产化妆品或食品工业的增值提取物。

更新日期:2020-05-24
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