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Islet cell transplantation in children.
Seminars in Pediatric Surgery ( IF 1.7 ) Pub Date : 2020-05-23 , DOI: 10.1016/j.sempedsurg.2020.150925
Appakalai N Balamurugan 1 , Deborah A Elder 2 , Maisam Abu-El-Haija 3 , Jaimie D Nathan 1
Affiliation  

This paper aims to provide an overview of islet cell transplantation in children, with specific attention to pediatric total pancreatectomy with islet autotransplantation (TPIAT). We will summarize the definition and causes of chronic pancreatitis in children, the TPIAT procedure and potential complications, the process of islet cell isolation and autotransplantation, and long-term results after TPIAT. Lastly, we will briefly discuss islet cell allotransplantation in the adult population and its potential role in treating children.



中文翻译:

儿童胰岛细胞移植。

本文旨在概述儿童胰岛细胞移植,特别关注小儿胰岛自体移植 (TPIAT) 全胰切除术。我们将总结儿童慢性胰腺炎的定义和原因、TPIAT 手术和潜在并发症、胰岛细胞分离和自体移植的过程以及 TPIAT 后的长期结果。最后,我们将简要讨论成人胰岛细胞同种异体移植及其在治疗儿童中的潜在作用。

更新日期:2020-05-23
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