A number of neurological disease complications have been seen following infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While most person with COVID-19 respiratory disease demonstrate headache, nausea and vomiting, up to 40% present also experience dizziness, confusion, cerebrovascular disease, muscle pain, ataxia and seizures. Loss of taste and smell, defects in visual acuity and pain occur in parallel. Such central nervous system (CNS) signs and symptoms linked to laboratory-confirmed SARS-CoV-2 infection is often life threatening. Health care providers currently evaluating patients with neurologic symptoms need consider COVID-19 in any differential diagnosis. These considerations will facilitate prompt testing, isolation and prevention of viral transmission speeding best clinical outcomes.

Graphical Abstract

中文翻译：

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SARS-CoV-2 感染导致神经功能障碍。

在感染严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 后，出现了许多神经系统疾病并发症。虽然大多数 COVID-19 呼吸道疾病患者表现出头痛、恶心和呕吐，但多达 40% 的患者还会出现头晕、精神错乱、脑血管疾病、肌肉疼痛、共济失调和癫痫发作。味觉和嗅觉丧失、视力缺陷和疼痛同时发生。这种与实验室确诊的 SARS-CoV-2 感染相关的中枢神经系统 (CNS) 体征和症状通常会危及生命。目前评估有神经系统症状患者的医疗保健提供者需要在任何鉴别诊断中考虑 COVID-19。这些考虑将有助于迅速检测、隔离和预防病毒传播，从而加速获得最佳临床结果。

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