In this study, we tested the feces of children with ASD and those of healthy children, and the overall changing of the gut fungal community was observed in ASD children compared with controls. However, there were no abundant fungi populations showed significant variations between the ASD and Control group both at phylum and class level. Among the 507 genera identified, Saccharomyces and Aspergillus showed significant differences between ASD (59.07%) and Control (40.36%), indicating that they may be involved in the abnormal gut fungal community structure of ASD. When analyzed at the species level, a decreased abundance in Aspergillus versicolor was observed while Saccharomyces cerevisiae was increased in children with ASD relative to controls. Overall, this study characterized the fungal microbiota profile of children with ASD and identified potential diagnostic species closely related to the immune response in ASD.

中文翻译：

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自闭症谱系障碍儿童肠道真菌菌群的营养不良。

在这项研究中，我们测试了ASD儿童和健康儿童的粪便，与对照组相比，在ASD儿童中观察到了肠道真菌群落的总体变化。但是，在门生和分类水平上，ASD和对照组之间没有大量的真菌种群显示出显着的差异。在鉴定的507个属中，酿酒酵母和曲霉在ASD（59.07％）和对照（40.36％）之间显示出显着差异，表明它们可能与ASD的肠道真菌群落结构异常有关。当在物种水平上进行分析时，与对照相比，ASD患儿中杂色曲霉的丰度降低，而酿酒酵母则增加。总体，