Anti-Leucine Glioma Inactivated 1 (LGI-1) autoimmune encephalitis (AE) is a rare neuroinflammatory brain condition. Individuals afflicted with this condition can present with cognitive and psychological manifestations that can impact the individual's quality of life, day to day functioning, independence, return to work and interpersonal relationships. Our knowledge of the cognitive profiles and disease associated psychopathology is severely lacking. This review provides a comprehensive summary of the currently available literature, conceptualising our current understanding of the neuropsychological manifestations of anti LGI-1 AE and summarises methodological limitations of the current research to inform and improve future investigations. Key Terms: Autoimmune Diseases; Neuroimmunology; Autoimmune Encephalitis, Limbic Encephalitis; Anti-LGI1 Encephalitis, LGI1; Neuropsychology, Cognitive Assessment.

中文翻译：

---

抗LGI1抗体介导的自身免疫性脑炎的神经心理谱

抗亮氨酸胶质瘤灭活 1 (LGI-1) 自身免疫性脑炎 (AE) 是一种罕见的神经炎症性脑病。患有这种疾病的个人可能会出现认知和心理表现，这些表现会影响个人的生活质量、日常功能、独立性、重返工作岗位和人际关系。我们严重缺乏对认知特征和疾病相关精神病理学的了解。本综述对当前可用的文献进行了全面总结，将我们目前对抗 LGI-1 AE 神经心理学表现的理解概念化，并总结了当前研究的方法学局限性，以告知和改进未来的调查。关键术语：自身免疫性疾病；神经免疫学；自身免疫性脑炎、边缘脑炎；抗 LGI1 脑炎，LGI1；神经心理学，认知评估。