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Recent clinical relevance of mono-genital colonization/infection by Ureaplasma parvum.
European Journal of Clinical Microbiology & Infectious Diseases ( IF 4.5 ) Pub Date : 2020-05-21 , DOI: 10.1007/s10096-020-03928-2
Víctor Siles-Guerrero 1 , Inmaculada Cardona-Benavides 2 , Carmen Liébana-Martos 3 , Fernando Vázquez-Alonso 4 , Manuela Expósito-Ruiz 5 , José María Navarro-Marí 6 , José Gutiérrez-Fernández 1, 6
Affiliation  

Ureaplasma parvum is the most prevalent genital mycoplasma in women of childbearing age. There is debate around the relevance of its presence in male or female genitals for disease development and as a cofactor. The objective of this study was to determine the prevalence of colonization/infection by U. parvum and its possible relationship with reproductive tract infections. We retrospectively analyzed the presence of U. parvum in patients referred by specialist clinicians for suspicion of genitourinary tract infection. U. parvum was detected in 23.8% of samples, significantly more frequently in females (39.9%) than in males (6%). Among the males, U. parvum was found alone in 68.4% of episodes, with Ct < 30. Among the females, U. parvum was detected in 88.6% of cases, with Ct < 30, including 22 cases with premature rupture of membranes and 6 cases with threat of preterm labor. Co-infection was significantly more frequent in females (62.6%) than in males (31.6%). Given the high prevalence of U. parvum as sole isolate in males and females with genitourinary symptoms, it should be considered in the diagnosis and treatment of genital infections, although its pathogenic role in some diseases has not been fully elucidated.

中文翻译:

小生殖性支原体单生殖器定植/感染的最新临床相关性。

在育龄妇女中,小额脲原体是最普遍的生殖道支原体。关于它在男性或女性生殖器中的存在与疾病发展以及作为辅助因子的相关性存在争议。这项研究的目的是确定U. parvum定植/感染的流行及其与生殖道感染的可能关系。我们回顾性分析了专科临床医生转诊怀疑存在泌尿生殖道感染的患者中的U. parvum。在23.8%的样本中检出U. parvum,女性(39.9%)的频率明显高于男性(6%)的频率。在男性中,仅在68.4%的发作中发现了小U. par。,而Ct <30。在女性中,88.6%的病例中发现了U. parvum,在Ct <30中,其中包括22例胎膜早破和6例有早产威胁的病例。女性(62.6%)的混合感染明显高于男性(31.6%)。鉴于在泌尿生殖道症状的男性和女性中,U。parvum是唯一的隔离株,尽管尚未完全阐明其在某些疾病中的致病作用,但仍应在诊断和治疗生殖器感染中予以考虑。
更新日期:2020-05-21
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