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A Study of Clinical Features and Risk Factors of Self-Referring Emergency Department Headache Patients: A Comparison with Headache Center Outpatients
European Neurology ( IF 2.4 ) Pub Date : 2020-01-01 , DOI: 10.1159/000505915
Alessandro Viganò 1 , Ersilia Savastano 2 , Barbara Petolicchio 2, 3 , Massimiliano Toscano 2, 4 , Rita De Sanctis 5, 6 , Ilaria Maestrini 2 , Vittorio Di Piero 2, 7
Affiliation  

Background: Nonlife-threatening headaches account for 3% of emergency department (ED) admissions, with social and economic negative consequences. We aim to investigate clinical features and risk factors of nonlife-threatening headache patients referring to ED versus those referring to headache outpatient clinics. Methods: During 6 months, we promptly reevaluated in our headache unit (HU) patients discharged from ED. We compared the clinical characteristics of patients who referred to ED with those of HU outpatients visited in the same time interval. Discriminant Function Analysis and Correspondence Analysis were used to determine risk factors for ED referral. Results: We recruited 49 post-ED patients and 126 outpatients. The main reasons for ED admission were poor response to acute treatment and aura-related symptoms. Headache diagnoses made in ED were generally not confirmed later (overall concordance of 47%), except for cluster headache (CH) and migraine with aura (MA). ED patients complained higher headache intensity, longer duration, and prolonged aura compared to outpatients. Aura was the main risk factor associated with ED admission on statistical models, while less prominent risk factors were sex, age, and years from migraine onset. Conclusions: ED patients presented a more severe headache clinical phenotype compared with outpatients. Headache diagnosis remains difficult in the emergency setting and is more easily achieved for the headache forms with standout features, such as MA or CH. According to statistical models, the aura is the most important risk factor for ED admissions.

中文翻译:

自转急诊科头痛患者的临床特征及危险因素研究:与头痛中心门诊患者的比较

背景:非危及生命的头痛占急诊科 (ED) 入院人数的 3%,具有社会和经济负面影响。我们旨在调查转诊至 ED 的非危及生命的头痛患者与转诊至头痛门诊的患者的临床特征和危险因素。方法:在 6 个月内,我们及时对从 ED 出院的头痛病房 (HU) 患者进行了重新评估。我们比较了转诊到 ED 的患者与在相同时间间隔内就诊的 HU 门诊患者的临床特征。判别函数分析和对应分析被用来确定急诊转诊的危险因素。结果:我们招募了 49 名 ED 后患者和 126 名门诊患者。ED 入院的主要原因是对急性治疗反应差和先兆相关症状。除了丛集性头痛 (CH) 和先兆偏头痛 (MA) 外,ED 中的头痛诊断通常没有得到证实(总体一致性为 47%)。与门诊患者相比,ED 患者抱怨更高的头痛强度、更长的持续时间和更长的先兆。在统计模型中,先兆是与 ED 入院相关的主要风险因素,而不太突出的风险因素是性别、年龄和偏头痛发作的年数。结论:与门诊患者相比,ED 患者表现出更严重的头痛临床表型。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。除了丛集性头痛 (CH) 和先兆偏头痛 (MA)。与门诊患者相比,ED 患者抱怨更高的头痛强度、更长的持续时间和更长的先兆。在统计模型中,先兆是与 ED 入院相关的主要风险因素,而不太突出的风险因素是性别、年龄和偏头痛发作的年数。结论:与门诊患者相比,ED 患者表现出更严重的头痛临床表型。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,例如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。除了丛集性头痛 (CH) 和先兆偏头痛 (MA)。与门诊患者相比,ED 患者抱怨更高的头痛强度、更长的持续时间和更长的先兆。在统计模型中,先兆是与 ED 入院相关的主要风险因素,而不太突出的风险因素是性别、年龄和偏头痛发作的年数。结论:与门诊患者相比,ED 患者表现出更严重的头痛临床表型。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。在统计模型中,先兆是与 ED 入院相关的主要风险因素,而不太突出的风险因素是性别、年龄和偏头痛发作的年数。结论:与门诊患者相比,ED 患者表现出更严重的头痛临床表型。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,例如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。在统计模型中,先兆是与 ED 入院相关的主要风险因素,而不太突出的风险因素是性别、年龄和偏头痛发作的年数。结论:与门诊患者相比,ED 患者表现出更严重的头痛临床表型。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。在紧急情况下,头痛诊断仍然很困难,对于具有突出特征的头痛形式,如 MA 或 CH,更容易实现。根据统计模型,先兆是 ED 入院最重要的危险因素。
更新日期:2020-01-01
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