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Schistosoma mansoni granulomas in the skeletal striated muscles in the murine model of neuroschistosomiasis: histological findings.
Memórias do Instituto Oswaldo Cruz ( IF 2.8 ) Pub Date : 2020-05-11 , DOI: 10.1590/0074-02760190383
Thiago Andre Alves Fidelis 1 , Geraldo Brasileiro-Filho 1 , Patricia M Parreiras 2 , Paulo Marcos Z Coelho 2 , Neusa Araujo 2 , Marco Vinicius Chaud 3 , Denicezar Angelo Baldo 3 , Nelson Brancaccio Dos Santos 4 , José Roberto Lambertucci 1
Affiliation  

Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly, liver abscesses, skinlesions, brain tumors and myeloradiculopathy. No lesions have been reported in skeletal striated muscles due to schistosomiasis mansoni in the literature. This short communication reports the histopathological findings on skeletal musculature in a murine model of neuroeschistosomiasis mansoni. Lesions were found in the tongue, masseter muscle, buccinator muscle, digastric muscle and temporalis muscle. Worm recovery was carried out to confirm the infection. We describe here, for the first time in the literature, injuries in the skeletal musculature due to Schistosoma mansoni nfection.

中文翻译:

神经血吸虫病小鼠模型中骨骼横纹肌的曼氏血吸虫肉芽肿:组织学发现。

曼氏血吸虫病在血吸虫向宿主体内迁移期间表现出许多临床表现,包括腹泻,肝肿大,脾肿大,肝脓肿,皮肤病,脑瘤和脊髓神经根病。在文献中,尚无因曼氏血吸虫病引起的骨骼横纹肌损伤的报道。这段简短的交流报道了曼氏神经血吸虫病小鼠模型中骨骼肌组织的组织病理学发现。在舌头,咬肌,腹部肌肉,腹肌和颞肌中发现病变。进行蠕虫恢复以确认感染。在本文中,我们首次描述了曼氏血吸虫感染对骨骼肌造成的损伤。
更新日期:2020-05-11
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