Previous studies in humans support the dual‐allergen exposure hypothesis, and several studies in mouse models have demonstrated that cutaneous exposure to disrupted or intact skin can lead to sensitization to peanut. However, the field lacks definitive evidence that cutaneous exposure leads to peanut allergy in humans or other primates.

中文翻译：

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应用于非人灵长类动物皮肤的花生会诱导抗原特异性 IgG，但不会诱导 IgE。

先前对人类的研究支持双重过敏原暴露假说，并且在小鼠模型中进行的几项研究表明，皮肤暴露于破损或完整的皮肤会导致对花生过敏。然而，该领域缺乏确定的证据表明皮肤接触会导致人类或其他灵长类动物对花生过敏。