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PDB-2-PBv3.0: An updated protein block database
Journal of Bioinformatics and Computational Biology ( IF 1 ) Pub Date : 2020-01-31 , DOI: 10.1142/s0219720020500092
Muthuvel Prasath Karuppasamy 1 , Suresh Venkateswaran 2 , Parthasarathy Subbiah 1
Affiliation  

Our protein block (PB) sequence database PDB-2-PBv1.0 provides PB sequences and dihedral angles for 74,297 protein structures comprising of 103,252 protein chains of Protein Data Bank (PDB) as on 2011. Since there are a lot of practical applications of PB and also as the size of PDB database increases, it becomes necessary to provide the PB sequences for all PDB protein structures. The current updated PDB-2-PBv3.0 contains PB sequences for 147,602 PDB structures comprising of 400,355 protein chains as on October 2019. When compared to our previous version PDB-2-PBv1.0, the current PDB-2-PBv3.0 contains 2- and 4-fold increase in the number of protein structures and chains, respectively. Notably, it provides PB information for any protein chain, regardless of the missing atom records of protein structure data in PDB. It includes protein interaction information with DNA and RNA along with their corresponding functional classes from Nucleic Acid Database (NDB) and PDB. Now, the updated version allows the user to download multiple PB records by parameter search and/or by a given list. This database is freely accessible at http://bioinfo.bdu.ac.in/pb3 .

中文翻译:

PDB-2-PBv3.0:更新的蛋白质块数据库

我们的蛋白质块 (PB) 序列数据库 PDB-2-PBv1.0 提供了截至 2011 年蛋白质数据库 (PDB) 的 103,252 条蛋白质链的 74,297 个蛋白质结构的 PB 序列和二面角。 PB 以及随着 PDB 数据库规模的增加,有必要提供所有 PDB 蛋白质结构的 PB 序列。截至 2019 年 10 月,当前更新的 PDB-2-PBv3.0 包含 147,602 个 PDB 结构的 PB 序列,包括 400,355 个蛋白质链。与我们之前的版本 PDB-2-PBv1.0 相比,当前的 PDB-2-PBv3.0蛋白质结构和链的数量分别增加了 2 倍和 4 倍。值得注意的是,它为任何蛋白质链提供 PB 信息,而不管 PDB 中蛋白质结构数据的缺失原子记录如何。它包括蛋白质与 DNA 和 RNA 的相互作用信息,以及来自核酸数据库 (NDB) 和 PDB 的相应功能类别。现在,更新版本允许用户通过参数搜索和/或给定列表下载多个 PB 记录。该数据库可在 http://bioinfo.bdu.ac.in/pb3 免费访问。
更新日期:2020-01-31
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