OBJECTIVE People with multiple sclerosis (PwMS) report greater emotion dysregulation, which is associated with increased symptoms of depression and anxiety, and reduced quality of life. Given the transdiagnostic significance of emotion dysregulation, the current study was designed to assess the feasibility and treatment effects of mindfulness meditation in reducing emotion dysregulation for PwMS. METHOD Sixty-one PwMS were randomized to 1 of 3 groups: 4-week mindfulness-based training (MBT), 4-week adaptive cognitive training (aCT), or a waitlist control group. Using self-report and behavioral measures, we examined the effects of MBT on emotion dysregulation, use of emotion regulation strategies, experience of negative and positive affect, and overall quality of life. RESULTS Mindfulness training was associated with reduced emotion dysregulation compared with the adaptive cognitive training and the waitlist control group (ηp² = .20). Relative to the waitlist group, the MBT group also demonstrated reductions on a composite score of preservative cognition, measuring rumination and worry (ηp² = .15). However, there was no differential use of emotion regulation strategies or between-groups differences in overall quality of life as a function of training. CONCLUSIONS Our pilot study provides preliminary support for MBT to reduce self-reported emotion dysregulation in PwMS. Given the widespread prevalence of mental health disturbances in this population, MBT can serve as a promising rehabilitation tool for PwMS (clinicaltrials.gov # NCT02717429). (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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多发性硬化症情绪失调的正念训练：一项试点随机对照试验。

目的 多发性硬化症 (PwMS) 患者报告情绪失调更严重，这与抑郁和焦虑症状增加以及生活质量降低有关。鉴于情绪失调的跨诊断意义，本研究旨在评估正念冥想在减少 PwMS 情绪失调方面的可行性和治疗效果。方法 将 61 名 PwMS 随机分配到 3 组中的 1 组：4 周正念训练 (MBT)、4 周适应性认知训练 (aCT) 或候补名单对照组。使用自我报告和行为测量，我们检查了 MBT 对情绪失调、情绪调节策略的使用、负面和正面影响的体验以及整体生活质量的影响。结果 与适应性认知训练和候补名单对照组 (ηp² = .20) 相比，正念训练与减少的情绪失调有关。相对于候补名单组，MBT 组还表现出在防腐认知、衡量反刍和担忧的综合评分上有所降低 (ηp² = .15)。然而，作为训练的函数，情绪调节策略的使用没有差异，也没有组间整体生活质量的差异。结论 我们的试点研究为 MBT 减少 PwMS 中自我报告的情绪失调提供了初步支持。鉴于该人群中普遍存在心理健康障碍，MBT 可以作为 PwMS 的一种有前途的康复工具 (clinicaltrials.gov # NCT02717429)。（PsycInfo 数据库记录 (c) 2020 APA，保留所有权利）。