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The Israeli Phage Bank (IPB).
Antibiotics ( IF 4.8 ) Pub Date : 2020-05-21 , DOI: 10.3390/antibiotics9050269
Ortal Yerushalmy 1 , Leron Khalifa 1 , Naama Gold 1 , Chani Rakov 1 , Sivan Alkalay-Oren 1 , Karen Adler 1 , Shira Ben-Porat 1 , Reut Kraitman 1 , Niv Gronovich 2 , Kerem Shulamit Ginat 2 , Mohanad Abdalrhman 3 , Shunit Coppenhagen-Glazer 1 , Ran Nir-Paz 3 , Ronen Hazan 1
Affiliation  

A key element in phage therapy is the establishment of large phage collections, termed herein “banks”, where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical phage microbiology, the prior treatment matching of phages and antibiotics to specific bacterial targets. A worldwide network of phage banks can promote a phage-based solution for any isolated bacteria. Herein, we describe the Israeli Phage Bank (IPB) established in the Hebrew University, Jerusalem, which currently has over 300 phages matching 16 bacteria, mainly pathogens. The phage bank is constantly isolating new phages and developing methods for phage isolation and characterization. The information on the phages and bacteria stored in the bank is available online.

中文翻译:

以色列噬菌体银行(IPB)。

噬菌体治疗的关键要素是建立大型噬菌体集合(在此称为“库”),其中存储了许多易于临床使用的,特征明确的噬菌体。这些噬菌体库可用于研究和临床目的。噬菌体库也是临床噬菌体微生物学中的关键要素,这是噬菌体和抗生素与特定细菌靶标的预先治疗匹配。全球噬菌体库网络可以促进针对任何分离细菌的基于噬菌体的解决方案。本文中,我们描述了在耶路撒冷希伯来大学建立的以色列噬菌体银行(IPB),该银行目前拥有300多种噬菌体,与16种细菌(主要是病原体)相匹配。噬菌体库不断地分离新的噬菌体,并开发用于噬菌体分离和表征的方法。
更新日期:2020-05-21
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