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Al(OTf)3‐Catalyzed Tandem Coupling Reaction between N,N‐Disubstituted Aminomalonitriles and Substituted Arenes: a Synthesis of 1‐Cyano‐bisindolylmethane Analogues≠
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2020-05-20 , DOI: 10.1002/adsc.202000261
Lin‐Sheng Lei 1 , Bo‐Wen Wang 1 , Da‐Ping Jin 1 , Zhu‐Peng Gao 1 , Huan‐Liang 1 , Shao‐Hua Wang 1, 2 , Xue‐Tao Xu 2 , Kun Zhang 2 , Xiao‐Yun Zhang 1
Affiliation  

A synthesis of 1‐cyano‐bisindolylmethane analogues via an Al(OTf)3‐catalyzed tandem coupling reaction between N,N‐disubstituted aminomalonitriles and substituted arenes has been developed. This method not only provides an alternative synthetic strategy for the synthesis of corresponding functional molecules, but also enriches the volume of bisarylmethanes library to facilitate related functional studies.

中文翻译:

N,N-双取代的氨基丙二腈和取代的芳烃之间的Al(OTf)3催化串联偶联反应:1-氰基-二吲哚基甲烷类似物的合成≠

的1-氰基bisindolylmethane类似物的合成通过的Al(OTF)3催化的串联耦合之间的反应N,N-二取代的aminomalonitriles和取代的芳烃已经研制成功。该方法不仅为合成相应的功能分子提供了另一种合成策略,而且丰富了双芳基甲烷库的体积,以方便相关的功能研究。
更新日期:2020-07-29
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