Vaccine development against SARS‐CoV‐2 has drawn attention around the globe due to the exploding pandemic. Although COVID‐19 is caused by a new coronavirus, SARS‐CoV‐2, previous research on other coronavirus vaccines, such as FIPV, SARS, and MERS, has provided valuable information for the rapid development of COVID‐19 vaccine. However, important knowledge gaps remain — some are specific to SARS‐CoV‐2, others are fundamental to immunology and vaccinology. Here, we discuss areas that need to be addressed for COVID‐19 vaccine development, and what can be learned from examples of vaccine development in the past. Since the beginning of the outbreak, the research progress on COVID‐19 has been remarkable. We are therefore optimistic about the rapid development of COVID‐19 vaccine.

中文翻译：

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COVID-19 疫苗：了解未知。

由于爆发性大流行，针对 SARS-CoV-2 的疫苗开发已引起全球关注。尽管 COVID-19 是由一种新型冠状病毒 SARS-CoV-2 引起的，但之前对 FIPV、SARS 和 MERS 等其他冠状病毒疫苗的研究为 COVID-19 疫苗的快速开发提供了宝贵的信息。然而，重要的知识差距仍然存在——一些是 SARS-CoV-2 特有的，另一些是免疫学和疫苗学的基础。在这里，我们讨论了 COVID-19 疫苗开发需要解决的领域，以及从过去的疫苗开发示例中可以学到什么。自疫情爆发以来，COVID-19 的研究进展显着。因此，我们对 COVID-19 疫苗的快速发展持乐观态度。