Functional genomics describes a field of biology that uses a range of approaches for assessing gene function with high-throughput molecular, genetic, and cellular technologies. The near limitless potential for applying these concepts to study the activities of all genetic loci has completely upended how today's cancer biologists tackle drug target discovery. We provide an overview of contemporary functional genomics platforms, highlighting areas of distinction and complementarity across technologies, so as to aid in the development or interpretation of cancer-focused screening efforts.

中文翻译：

---

用于癌症药物靶标发现的功能基因组学。

功能基因组学描述了一个生物学领域，该领域使用多种方法通过高通量分子，遗传和细胞技术评估基因功能。应用这些概念来研究所有遗传基因座的活动具有近乎无限的潜力，这完全颠覆了当今的癌症生物学家应对药物靶标发现的方式。我们提供了当代功能基因组学平台的概述，突出了各种技术之间的区别和互补性，以帮助开发或解释针对癌症的筛查工作。