This paper presents a comprehensive techno‐economic evaluation of an integrated natural deep eutectic solvent (NADES)‐based biorefinery – a 1 ton day⁻¹ capacity design plant. The key parameters include payback period, net present value (NPV), and internal rate of return (IRR). These were compared with the parameters of conventional biorefineries. The ‘n th plant’ results clearly revealed that the single product‐based biorefinery is not a sustainable approach. Hence, value‐added products viz ., cellulose, lignin, xylan, silica, etc ., play a vital role in the cost‐effectiveness of bio‐based biorefineries. Based on ‘base‐case’ experimental results, a pilot‐scale plant design scenario is most feasible, with a NPV of 1.4 million USD, >100% IRR, and a payback period of <2 years. Sensitivity analysis revealed that lignin has the greatest impact on revenue. This report proves that multi‐product biorefineries provide better sustainability. The concepts of solvent recycling and reuse, and key challenges to the commercialization of this design approach, were also discussed. The application of NADES in biorefineries, has several advantages, making the implementation of NADES a key feature for increased sustainability in this industry. © 2020 Society of Chemical Industry and John Wiley & Sons, Ltd

中文翻译：

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天然深共溶剂有机精炼厂的技术经济评估：探索不同的设计方案

本文介绍了基于集成的天然深共晶溶剂（NADES）的生物精炼厂的综合技术经济评估^-1吨日^-1能力设计工厂。关键参数包括投资回收期，净现值（NPV）和内部收益率（IRR）。将这些与常规生物精炼厂的参数进行了比较。第n家工厂的结果清楚地表明，基于单一产品的生物精炼厂不是可持续的方法。因此，增值产品即纤维素，木质素，木聚糖，二氧化硅等在生物基生物精炼厂的成本效益中起着至关重要的作用。根据“基础案例”实验结果，中型规模工厂设计方案是最可行的，NPV为140万美元，IRR大于100％，投资回收期小于2年。敏感性分析表明，木质素对收入的影响最大。该报告证明，多产品生物炼油厂可提供更好的可持续性。还讨论了溶剂回收和再利用的概念，以及该设计方法商业化的主要挑战。NADES在生物精炼厂中的应用具有多个优势，这使NADES的实施成为提高该行业可持续性的关键特征。©2020年化学工业协会和John Wiley＆Sons，Ltd