In contrast to lymph nodes, the lymphoid regions of the spleen-the white pulp-are located deep within the organ, yielding the trafficking paths of T cells in the white pulp largely invisible. In an intravital microscopy tour de force reported in this issue of Immunity, Chauveau et al. show that T cells perform unidirectional, perivascular migration through the enigmatic marginal zone bridging channels.

中文翻译：

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T细胞：通向白浆的桥梁和通道。

与淋巴结相反，脾脏的淋巴样区域（白色牙髓）位于器官深处，从而在白色牙髓中产生了T细胞的运输途径，这在很大程度上是不可见的。Chauveau等人在本期《免疫》杂志中报道了一项活体显微镜检查。结果表明，T细胞通过神秘的边缘区桥接通道进行单向血管周围迁移。