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Synthesis, Characterization and Antimicrobial Evaluation of Piyar Gum-Induced Silver Nanoparticles
National Academy Science Letters ( IF 1.1 ) Pub Date : 2020-05-20 , DOI: 10.1007/s40009-020-00982-4
Mahtab Z. Siddiqui , Arnab Roy Chowdhury , Bhoj Raj Singh , Sudarshan Maurya , Niranjan Prasad

Buchanania lanzan gum commonly known as char, achar, piyar and chironji is a naturally occurring water-soluble, edible polysaccharide derived from the bark of Buchanania lanzan Spreng. Silver nanoparticles have been synthesized using Buchanania lanzan gum exudates adopting green synthesis methodology and characterized by UV–Vis, Fourier transform infrared spectroscopy, zeta potential and particle size analysis, scanning electron microscopy, transmission electron microscopy and atomic force microscopy confirming the synthesis of AgNPs. The synthesized piyar gum-induced AgNPs are spherical in shape, small enough in size (14.74–19.86 nm) and noncytotoxic. Evaluation of bactericidal activity of synthesized piyar gum-induced AgNPs against 17 strains of 14 Gram-negative and Gram-positive bacterial pathogens, using agar well diffusion method, exhibited strong bactericidal activity against Gram-negative bacterial pathogens. The minimum inhibitory concentration against two Gram-negative bacterial strains, i.e., Escherichia coli and Avibacterium avium, was found to be 0.52 µg/mL and 0.53 µg/mL, respectively, which was at par with that of positive control (0.5 mM silver nitrate solution).



中文翻译:

皮亚尔胶诱导的银纳米粒子的合成,表征及抗菌性能评价

Buchanania lanzan口香糖通常称为characharpiyarchironji,是一种天然存在的水溶性可食用多糖,衍生自Buchanania lanzan Spreng的树皮。使用绿色绿色合成方法,使用Buchanania lanzan胶渗出液合成了银纳米颗粒,并通过UV-Vis,傅立叶变换红外光谱,ζ电位和粒度分析,扫描电子显微镜,透射电子显微镜和原子力显微镜表征了银纳米颗粒,从而证实了AgNPs的合成。合成皮亚尔口香糖诱导的AgNPs呈球形,大小足够小(14.74-19.86 nm),无细胞毒性。使用琼脂良好扩散方法评估合成的皮亚尔胶诱导的AgNPs对17株14种革兰氏阴性和革兰氏阳性细菌病原体的杀菌活性,表现出对革兰氏阴性细菌病原体的强杀菌活性。发现对两种革兰氏阴性细菌菌株,即大肠杆菌鸟杆菌的最小抑菌浓度分别为0.52 µg / mL和0.53 µg / mL,与阳性对照(0.5 mM硝酸银)相当。解)。

更新日期:2020-05-20
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