当前位置: X-MOL 学术Synlett › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Copper-Catalyzed Asymmetric Intermolecular N-Monoarylation of Unprotected Sulfonamides via Desymmetrization of Diaryliodonium Salts at Room Temperature
Synlett ( IF 2 ) Pub Date : 2020-05-19 , DOI: 10.1055/s-0040-1707121
Xiao Jin , Xiu-Ling Yu , Wen-Qiang Yang , Yan-Li Li , Chun Zhang , Zhen Wang , Hui-Zhen Zhang

A copper-catalyzed asymmetric intermolecular N-monoarylation of weakly nucleophilic sulfonamide by desymmetrization of cyclic diaryliodonium salts has been developed. Chiral copper(II)–diamine ligand complexes catalyzed this intermolecular asymmetric aryl C–N cross-coupling reaction effectively at room temperature to afford a series of N-monoarylsulfonamides in good to excellent yields and enantioselectivities.

中文翻译:

通过在室温下二芳基碘盐的去对称化铜催化的未保护磺酰胺的不对称分子间 N-单芳基化

通过环状二芳基碘鎓盐的去对称化,已开发出铜催化的弱亲核磺酰胺的不对称分子间 N-单芳基化。手性铜(II)-二胺配体配合物在室温下有效地催化了这种分子间不对称芳基C-N交叉偶联反应,以良好至极好的产率和对映选择性提供了一系列N-单芳基磺酰胺。
更新日期:2020-05-19
down
wechat
bug