In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 is the best singlet oxygen generator and the most phototoxic (at 2.5 μM) towards B16F10 cells.

中文翻译：

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使用氮杂双嘧啶酮作为光敏剂对黑素瘤细胞进行光动力治疗。

在这项研究中，我们首次报告了四种氮杂二吡咯烷酮（ADPM）作为癌症PDT的光敏剂的用途。评估了ADPM的合成，表征及其对B16F10黑色素瘤细胞的光动力作用。ADPM 2是对B16F10细胞最好的单线态氧产生剂，也是最具光毒性的（2.5μM）。