Radiofrequency ablation (RFA) is a clinical technique which inactivates targeted biological tissues by heating to remove tumors or to cure diseases like atrial fibrillation. Temperature is a fundamental parameter for ablation dose control and treatment effect evaluation. This paper presents the design, fabrication and characterization of an all-optical fiber ultrasound temperature measurement probe. The novelty of this probe is to both generate and receive ultrasound optically through fibers. The ultrasound generation was achieved with a $425~\mu \text{m}$ multi-mode fiber based on photoacoustic (PA) principle and the receiving part applied a $125~\mu \text{m}$ single mode fiber with a Fabry–Pérot (FP) interferometer on its tip. The temperature was measured through detecting the time-of-flight (TOF) of the reflected ultrasound pulses. The probe’s feasibility of measuring temperature during ablation had been verified in vitro while excised bovine liver tissue was used as the ultrasound reflector.

中文翻译：

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用于射频消融温度监测的光纤超声探头：体外结果

射频消融 (RFA) 是一种临床技术，通过加热使目标生物组织失活以去除肿瘤或治疗心房颤动等疾病。温度是消融剂量控制和治疗效果评估的基本参数。本文介绍了全光纤超声温度测量探头的设计、制造和表征。这种探头的新颖之处在于通过光纤以光学方式产生和接收超声波。超声波的产生是通过一个 $425~\mu \text{m}$ 基于光声 (PA) 原理的多模光纤和接收部分应用了 $125~\mu \text{m}$ 单模光纤，其尖端带有法布里-珀罗 (FP) 干涉仪。通过检测反射超声脉冲的飞行时间 (TOF) 来测量温度。该探头在消融过程中测量温度的可行性已在体外得到验证，同时切除的牛肝组织用作超声反射器。