Abstract In this work, the coupling phase change heat transfer process and thermal stress behavior of biological tissue during cryosurgery are studied in the context of a generalized thermoelastic theory. The nonlinear governing equations are constructed while considering the variable thermal properties and solved by a time-domain finite element method based on the effective heat capacity formulation. A 2-D tumor and normal tissue model is adopted for simulating the freezing process in cryosurgery. The effects of temperature-dependent thermal properties and relaxation time on the responses of biological tissue are discussed and illustrated graphically.

中文翻译：

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冷冻手术过程中具有可变热特性的生物组织的相变热弹性分析

摘要 在这项工作中，在广义热弹性理论的背景下，研究了冷冻手术过程中生物组织的耦合相变传热过程和热应力行为。非线性控制方程是在考虑可变热特性的同时构建的，并通过基于有效热容公式的时域有限元方法求解。采用二维肿瘤和正常组织模型来模拟冷冻手术中的冷冻过程。温度相关的热特性和弛豫时间对生物组织响应的影响进行了讨论和图示。