With the gradual reduction of emissions from building products, emissions from human occupants become more dominant indoors. The impact of human emissions on indoor air quality is inadequately understood. The aim of the Indoor Chemical Human Emissions and Reactivity (ICHEAR) project was to examine the impact on indoor air chemistry of whole‐body, exhaled, and dermally emitted human bioeffluents under different conditions comprising human factors (t‐shirts/shorts vs long‐sleeve shirts/pants; age: teenagers, young adults, and seniors) and a variety of environmental factors (moderate vs high air temperature; low vs high relative humidity; presence vs absence of ozone). A series of human subject experiments were performed in a well‐controlled stainless steel climate chamber. State‐of‐the‐art measurement technologies were used to quantify the volatile organic compounds emitted by humans and their total OH reactivity; ammonia, nanoparticle, fluorescent biological aerosol particle (FBAP), and microbial emissions; and skin surface chemistry. This paper presents the design of the project, its methodologies, and preliminary results, comparing identical measurements performed with five groups, each composed of 4 volunteers (2 males and 2 females). The volunteers wore identical laundered new clothes and were asked to use the same set of fragrance‐free personal care products. They occupied the ozone‐free (<2 ppb) chamber for 3 hours (morning) and then left for a 10‐min lunch break. Ozone (target concentration in occupied chamber ~35 ppb) was introduced 10 minutes after the volunteers returned to the chamber, and the measurements continued for another 2.5 hours. Under a given ozone condition, relatively small differences were observed in the steady‐state concentrations of geranyl acetone, 6MHO, and 4OPA between the five groups. Larger variability was observed for acetone and isoprene. The absence or presence of ozone significantly influenced the steady‐state concentrations of acetone, geranyl acetone, 6MHO, and 4OPA. Results of replicate experiments demonstrate the robustness of the experiments. Higher repeatability was achieved for dermally emitted compounds and their reaction products than for constituents of exhaled breath.

中文翻译：

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室内化学人的排放和反应性（ICHEAR）项目：实验方法概述和初步结果。

随着建筑产品排放物的逐渐减少，室内人员的排放物在室内变得越来越占主导地位。人们对人类排放物对室内空气质量的影响了解不足。室内化学物质人类排放和反应性（ICHEAR）项目的目的是研究在包括人为因素（T恤衫/短裤与长衫袖衬衫/裤子；年龄：青少年，年轻人和老年人）和各种环境因素（中等或较高的气温；较低或较高的相对湿度；存在与否的臭氧）。在一个控制良好的不锈钢恒温箱中进行了一系列人体实验。最先进的测量技术用于量化人类排放的挥发性有机化合物及其总OH反应性；氨，纳米颗粒，荧光生物气溶胶颗粒（FBAP）和微生物排放物；和皮肤表面化学。本文介绍了该项目的设计，方法和初步结果，比较了五个小组进行的相同测量，每个小组由4名志愿者组成（2名男性和2名女性）。志愿者穿着相同的洗过的新衣服，并被要求使用同一套不含香料的个人护理产品。他们在无臭氧（<2 ppb）的房间中呆了3个小时（早上），然后离开了10分钟的午餐时间。志愿者返回暗室10分钟后，将臭氧（占用的暗室中目标浓度约为35 ppb）引入，并且测量继续进行了2.5个小时。在给定的臭氧条件下，五组之间的香叶基丙酮，6MHO和4OPA的稳态浓度观察到相对较小的差异。丙酮和异戊二烯的变异性较大。臭氧的存在与否显着影响丙酮，香叶基丙酮，6MHO和4OPA的稳态浓度。复制实验的结果证明了实验的鲁棒性。与呼气成分相比，真皮释放的化合物及其反应产物的重复性更高。丙酮和异戊二烯的变异性较大。臭氧的存在与否显着影响丙酮，香叶基丙酮，6MHO和4OPA的稳态浓度。复制实验的结果证明了实验的鲁棒性。与呼气成分相比，真皮释放的化合物及其反应产物的重复性更高。丙酮和异戊二烯的变异性较大。臭氧的存在与否显着影响丙酮，香叶基丙酮，6MHO和4OPA的稳态浓度。复制实验的结果证明了实验的鲁棒性。与呼气成分相比，真皮释放的化合物及其反应产物的重复性更高。