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Modulation of β-catenin levels regulates cranial neural crest patterning and dispersal into first pharyngeal arch.
Developmental Dynamics ( IF 2.5 ) Pub Date : 2020-05-19 , DOI: 10.1002/dvdy.208
Alok Javali 1, 2 , Vairavan Lakshmanan 2, 3 , Dasaradhi Palakodeti 2 , Ramkumar Sambasivan 2, 4
Affiliation  

Vertebrate cranial neural crest cells (CNCCs) are multipotent, proximal to the source CNCC form the cranial ganglia. Distally, in the pharyngeal arches, they give rise to the craniofacial skeleton and connective tissues. Fate choices are made as CNCC pattern into distinct destination compartments. In spite of this importance, the mechanism patterning CNCC is poorly defined.

中文翻译:

β-连环蛋白水平的调节调节颅神经嵴图案形成和扩散到第一咽弓。

脊椎动物颅神经嵴细胞 (CNCC) 是多能的,靠近来自颅神经节的源 CNCC。在远端,在咽弓中,它们产生颅面骨骼和结缔组织。命运选择作为 CNCC 模式进入不同的目的地隔间。尽管如此重要,但 CNCC 的机制模式定义不明确。
更新日期:2020-05-19
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