We investigated pneumococcal carriage between children ≦5 years old with otitis media (OM) and those without. Non-PCV13 serotypes were common in both groups; 19A remained the second most common serotype among children with OM despite high PCV13 coverage. This is important when considering a schedule with reduced vaccine doses or reduced valency, and the modification of pneumococcal immunization schedule should be followed up closely to monitor the result of protection against pneumococcal infections.

中文翻译：

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患有中耳炎的儿童与没有肺炎球菌结合疫苗的儿童之间的血清型分布不同。

我们调查了5岁以下患有中耳炎（OM）的儿童与没有中耳炎的儿童之间的肺炎球菌携带情况。两组均非PCV13血清型。尽管PCV13覆盖率高，但19A仍是OM儿童中第二常见的血清型。当考虑减少疫苗剂量或减少效价的时间表时，这一点很重要，应密切跟进修改肺炎球菌免疫计划，以监测预防肺炎球菌感染的结果。