Abstract

The antimicrobial activity of the new nonribosomal peptide emericellipsin A against biofilm-forming, pathogenic, gram-positive and gram-negative clinical bacteria was studied. It was shown for the first time that peptides from the group of peptaibols can inhibit pathogenic forms of bacteria via their effect on biofilm formation. The most pronounced effect was demonstrated in relation to gram-positive bacteria.

中文翻译：

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分离的拟南芥脂肽Emericellipsin A对形成生物膜的细菌的抗微生物活性。

摘要

研究了新型非核糖体肽E的神经肽素A对生物膜形成，致病性，革兰氏阳性和革兰氏阴性临床细菌的抗菌活性。首次显示肽肽组的肽可以通过其对生物膜形成的作用来抑制细菌的致病形式。与革兰氏阳性细菌有关，显示出最明显的作用。