Pregnant travelers face numerous risks, notably increased susceptibility to or severity of multiple infections, including malaria. Because pregnant women residing in areas non-endemic for malaria are unlikely to have protective immunity, travel to endemic areas poses risk of severe illness and pregnancy complications, such as low birthweight and fetal loss. If travel to malaria-endemic areas cannot be avoided, preventive measures are critical. However, malaria chemoprophylaxis in pregnancy can be challenging, since commonly used regimens have varying levels of safety data and national guidelines differ. Furthermore, although chloroquine and mefloquine have wide acceptance for use in pregnancy, regional malaria resistance and non-pregnancy contraindications limit their use. Mosquito repellents, including N,N-diethyl-m-toluamide (DEET) and permethrin treatment of clothing, are considered safe in pregnancy and important to prevent malaria as well as other arthropod-borne infections such as Zika virus infection. Pregnant travelers at risk for malaria exposure should be advised to seek medical attention immediately if any symptoms of illness, particularly fever, develop.

中文翻译：

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孕妇中有疟疾。

怀孕的旅行者面临众多风险，特别是对包括疟疾在内的多种感染的易感性或严重性增加。由于居住在非疟疾流行地区的孕妇不太可能具有保护性免疫力，因此前往流行地区旅行会带来重病和怀孕并发症（例如低出生体重和胎儿丢失）的风险。如果无法避免前往疟疾流行地区，则必须采取预防措施。但是，由于通常使用的治疗方案的安全性数据水平各不相同，并且国家指南有所不同，因此妊娠期疟疾的化学预防可能具有挑战性。此外，尽管氯喹和甲氟喹已被广泛用于妊娠，但是局部疟疾抵抗力和非妊娠禁忌症限制了它们的使用。驱蚊剂，包括N，N-二乙基间甲苯胺（DEET）和氯菊酯对衣物的处理被认为在怀孕期间安全，对于预防疟疾以及其他节肢动物传播的感染（例如寨卡病毒感染）非常重要。如果出现任何疾病症状，特别是发烧，应建议有疟疾风险的孕妇旅客立即就医。